Wear nitrile gloves, eye protection, and a Tyvek or disposable coverall to keep resin and glass fibers off your skin and clothes. Use an organic-vapor respirator when working with polyester resin, gelcoat, MEKP, or solvents, and always keep the area ventilated. A simple dust mask is enough only for sanding cured glass, not for liquid resin or solvent fumes.

Use disposable nitrile gloves, not latex or vinyl. Nitrile resists the styrene in polyester and the chemicals in epoxy far better, and it lowers the risk of the skin sensitivity that repeated epoxy contact can bring on. Change gloves as soon as resin gets on the outside, and do not wipe resin off with acetone while wearing them, which can carry it through to your skin.